Radioimmunoassay for urinary renal tubular antigen: A potential marker of tubular injury
نویسندگان
چکیده
منابع مشابه
Autophagy activation reduces renal tubular injury induced by urinary proteins
Autophagy is shown to be beneficial for renal tubular injury caused by nephrotoxic drugs. To investigate whether autophagy could protect renal tubular epithelial cells (TECs) from injury induced by urinary proteins, we studied the activity and action of autophagy in TECs after urinary protein overload in vivo and in vitro. We found that autophagic vacuoles increased in TECs from patients with m...
متن کاملAntioxidant properties of repaglinide and its protections against cyclosporine A-induced renal tubular injury
Objective(s): Repaglinide (RG) is an antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus. It has a good safety and efficacy profile in diabetic patients with complications in renal impairment and is an appropriate treatment choice, even for individuals with more severe degrees of renal malfunctions. The aim of the present study was to examine the protective...
متن کاملUrinary β2-Microglobulin is a Sensitive Indicator for Renal Tubular Injury
domain of the immunoglobulin molecule [3]. β2-microglobulin forms the invariant light chain portion of major histocompatibility complex (MHC) class I molecules [4-6], which can be found on the membrane of all nucleated cells [7]. Thus, cellular membrane turnover is the main source of serum β2-microglobulin [3]. Because of its small size, β2-microgloUrinary β2-Microglobulin is a Sensitive Indica...
متن کاملRenal tubular injury associated with anagrelide use.
A 60-year-old man with a 35 year history of Crohn’s disease was diagnosed with essential thrombocytosis (ET) following a unilateral renal artery thrombosis in May 2003. His platelet count at the time of diagnosis with ET was 1.3 million cells/mm. He began taking 0.5mg oral anagrelide twice daily, increasing the dose to 1mg each morning and 0.5mg each evening over the next weeks and, finally, to...
متن کاملParacetamol-induced renal tubular injury: a role for ER stress.
Paracetamol (also known as acetaminophen) causes acute and chronic renal failure. While the mechanisms leading to hepatic injury have been extensively studied, the molecular mechanisms of paracetamol-induced nephrotoxicity are poorly defined. Paracetamol induced cell death with features of apoptosis in murine proximal tubular epithelial cells. While paracetamol increased the expression of the d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Kidney International
سال: 1978
ISSN: 0085-2538
DOI: 10.1038/ki.1978.73